Metformin
Drug of choice
Decreases gluconeogenesis
Increases peripheral utilisation of glucose
Only affective if Beta-cell capacity remains.
Common GI side-affects
Can be used for treatment of PCOS
Contra-indicated with renal failure - leads to lactic acidosis
Sulponylureas
Increase the excretion of insulin.
Only affective if Beta-cell capacity remains.
Can encourage weight gain.
Nateglinide & Repaglinide
Similar to Sulphonureas
Acarbose
Inhibits absorption of starch and sucrose
Can cause flatulence
Thiazolidinediones
Relatively new
Increase peripheral insulin sensitivity
Can cause weight gain
Subscribe to:
Post Comments (Atom)
No comments:
Post a Comment